In most cases, these decreases in heritability were due to a greater decrease of genetic variance than of residual variance.
In addition, CCEmin should be preferred to approximate and sample entropies: indeed, approximate entropy provides a biased estimate of complexity [9] and to sample entropy necessitates an arbitrary selection of the pattern length L. Older subjects revealed significant changes of time domain parameters, i.e. an increase of heart rate and a decrease of total variance compared to young subjects.
Removing of either the two placental factors or chorionicity resulted in a decrease of genetic variance and decrease of heritability.
Clearly, for all solutions dead time of the TCSPC system yields slower decrease of the variance as found in theory (Fig. 3) at the cost of lower SNR.
In contrast, whenever the population size or the number of loci is finite, predictions include a decrease of genetic variance and of the response to selection until a steady state is reached, i.e. selection/mutation/drift equilibrium [ 20].
From computation, a sample size of 400 patients would have been sufficient, but we had to take the cluster effect into account, related to the fact that the patients were recruited in different practices (adjustment taking into account the artificial decrease of the variance of measures collected in the same practice).
A sample size of 400 patients would have been sufficient, but we had to take the cluster effect into account, related to the fact that the patients were recruited in different practices (adjustment for taking into account the artificial decrease of the variance of measures collected in the same practice).
Based on these assumptions Eq. (11) is rewritten as: 〈 I ¯ (T ) 2 〉 − 〈 I ¯ (T ) 〉 2 = δ 2 T 2 ∫ 0 T (T − t δ ) F e − t δ / τ r d t = 2 F τ r T 2 { T − τ r + e − T δ / τ r [ τ r + (δ − 1 ) ] } (14 According to Eq. (14), dead time yields slower rate of decrease of the variance of the time-averaged intensity.
Plotting the average across units of this index, which reflects the decrease of the variance in the angles between triplets, already observed in Figure 6, we see again, that after roughly 4 million time steps the system is already arranged in a stable ordered manner, with equilateral triangles among neighboring fields that dominate the activity pattern.
