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Glycerol alleviated the activity decrease of the key enzymes in the mixture.
Despite the marked decrease of the key enzymes involved in oxidative phosphorylation, the ATP level in the Al-stressed cells did not undergo a corresponding reduction.
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Several faults could cause the decreasing evaluation of the key performance indicators (KPIs).
In addition, IWP-2 treatment resulted in decreased expression of the key EMT transcription factors, Vimentin and Twist.
Though no studies have focussed on older patients, higher proportions of registered nurses and lower workloads have been associated with decreased levels of the key complications [ 12].
More recently, it was shown that tellurite-exposed E. coli exhibits decreased activity of the key glycolytic enzymes pyruvate kinase (PK) and phosphofructokinase (PFK) [ 27].
Furthermore, decreased expression of the key erythroid signaling protein KIT was detected in fetal liver cells of a RPS19-deficient mouse, which may contribute to the erythroid failure in DBA.
This reduction was accompanied by elevated rates of apoptosis, which correlated with decreased expression of the key anti-apoptotic factor BCL-2 [ 43]. miR-21 has been identified as being upregulated in glioblastomas, and miR-21 knockdown in glioblastoma cell lines results in caspase activation and elevated apoptotic rates, indicating a pro-survival function for miR-21 [ 44- 48].
The hypothermia-associated decrease of the metabolic rate in key organs is supposed to be one of the most protective strategies for cellular function during periods of haemorrhage, ischemia and reperfusion.
The impacts of glutamate on the central metabolism of P. pastoris G1HL was inferred to be modulated through the increase and/or decrease of the metabolite concentrations in key nodes together with the energy and redox status in order to meet the increased demands of redox cofactors and energy for higher β-galactosidase production on Glc/Glu.
In contrast, the age-dependent decrease of both key mitochondrial proteins and bioenergetic competence is considerably attenuated in daf-2 e1370) daf-2 e1370ls.
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