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It should be noted that in order to align the sequences of these 3D patterns (ASP637, PRO671, SER636, GLU638 and ARG641 to the Atom459, and ASP114, PRO113, SER115, GLU70 and ARG112 to Atom151), a sequence-based method must incorporate at least 40 gaps, with the corresponding decrease of the alignment significance.
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A large amount of false peaks, i.e. noise detected as peaks by the peak detection algorithm, may decrease the quality of the alignment.
For distantly-related proteins, however, both the sequence similarity and the alignment length are often reduced, resulting in a decreased statistical significance of the alignment.
Using these quality values also decreases the speed of the alignment [ 9].
So, an increase in the evolutional distance between homologous regions of sequences causes a noticeable decrease in the quality of global alignment, a considerable decrease of the quality of global alignment taking place at a decreasing length of consoles and a diminishing shift of the core from the center of sequences.
The increase of seeds uniqueness induces the decrease of seed alignment false rate.
We see, in particular, a slight decrease in the amplitude of the alignment with the number of cycles, indicating that fiber plasticity still occurs, although on much larger timescales.
22 The rate of the decrease of the circularity index and alignment angle follows the time course for HS upregulation under laminar shear stress (Fig 4).
The number of excluded nrESS decreases as the alignment score increases.
However, when the flow rate increases up to 1000 μL min−1, the density and degree of the alignment of the nanowires decrease.
The quality of the alignment and SNP prediction decreases as the number of inaccurate base calls increase.
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