Sentence examples for decrease of drug from inspiring English sources

For asthma patients, it is necessary to weigh the benefit/risk ratio of a higher flow with higher respiratory support but probably with a decrease of drug delivery.

Increasing the covered area of the core tablet results in a decrease of drug release since the cover hindrances the contact of the liquid with the core surface and modifies its dissolution and consequently its release.

Resistance to chemotherapy is related to the overall mechanisms that are involved in a decrease of drug efficacy against tumours [ 9].

Future research is needed, however, to determine if a specific cause and effect relationship exists between the implementation of a PCIP and the decrease of drug diversion.

Hence, our results suggest that standardized herbal extract can decrease the CYP3A4 activity in vivo and may participate in clinically significant interactions with drugs metabolized by this enzyme, since the inhibition of the CYP3A4 enzyme causes a decrease of drug metabolism leading to an undesirable pharmacological effect and the appearance of toxic symptoms of overdose.

Since the chromatograms did not show additional peaks and a significant decrease of drug content was not observed (assays between 98.17 and 100.80%), it seems that the ethylenediamine degradant requires an exposure time and/or intensity higher than the used in this research to be significantly formed.

Decrease of drug-resistant cell viability after C60 photoexcitation corresponded to a significant drop of mitochondrial potential.

Given the current, fair, rate of virologic and immunologic successes of first-line anti-HIV antiretroviral therapies in the European Union and other developed countries [ 29- 32], along with the decrease of drug-resistance prevalence [ 33- 39], the objective is now the prolongation of the therapy duration with the minimization of adverse events.

The decrease of drugs consumption during a trip is in contradiction with the results of previous studies.

Moreover, persons who travel to Central Europe and Western Europe have a higher consumption of drugs than the average, which may explain the decrease of drugs consumption during a trip to other regions of the world.

Age-related changes in body composition can result in increases or decreases of drug volume distribution, and hepatic or renal dysfunction can impair drug metabolism and drug clearance [ 1369, 1370].