As the SC-BLSOM reduces the map size in proportion to the decrease of input data, plotting the original input data produces approximately four data pieces per one node, resulting in a density twice that of the conventional BLSOM.
In other words, increasing exposure period from 4 up to 14 days did not consistently increase or decrease variability of data, except at low concentrations (see below).
So, the ZP method is based on the decrease of the data transmission efficiency.
Other non-coherent modulation schemes have been proposed to overcome the decrease of the data rate and to improve the system performance.
Our own ATP measurements during 200 and 500 μM TLC-S stimulation did not prove a pronounced decrease of ATP (data not shown).
Our simulations strongly support that multiplexing experimental designs improve TPR and FPR while greatly reducing the cost of the experiment, as the benefits of multiplexing n-biological replicates far outweigh the decrease of available data per sample by 1/ n.
The increased span size may be due in part to the decreased amount of data.
The statistical power is reduced with decreasing amount of data and it is therefore important to retain as much data as possible.
In the long term, the registry aims to extract from administrative systems and involve direct database entry with validation rules included, which should result in decreased duplication of data collection and reduced error.
