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Once antibiotic MDA is being scaled up, it is expected to rapidly decrease infection levels while the decline in symptoms of clinical disease will be more gradually.
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Disruption of the CRE element of P4 drastically decreased infection levels without altering range.
They also decreased infection levels of M. javanica on tomato between 29 and 93% (Moosavi et al. 2010).
While Sp110 mRNA levels increased concurrently with A. phagocytophilum infections in HL-60 cells, the silencing of Sp110 expression by RNA interference resulted in decreased infection levels.
Although (A_{1}) does not affect the number of (R_{0}), reducing (A_{1}) can decrease the infection level of (I_{2}) (see Figure 4).
Antibiotic treatment decreased infection.
Generation 16 displayed only a 27% decrease in infection level (Fig. 1b and Additional File 3 Table).
Knocking down IRF-1 with siRNA decreased the HIV-1 infection levels, whereas the IRF-7 knockdown increased HIV-1 infection levels.
Despite the fact that individual variation in gene expression affected the statistical significance of results, silencing of the genes encoding for putative von Willebrand factor (94Will), flagelliform silk protein (100Silk) and subolesin (4D8) resulted in 63%, 79% and 60% decrease in A. marginale infection levels in R. microplus male salivary glands, respectively (Table 1).
TNFα mRNA in the brain was increased at 4 days p.i. (Figure 3), reached the highest level at 10 days p.i., and then decreased to pre-infection levels by 14 days p.i.
Expression levels in gill tissue fluctuated over the time course, with up-expression at 3 h (9 fold), reduced levels of expression at 6 h and 12 h, increasing to the highest level at 24 h (11 fold), remaining high at 48 h (8 fold), decreasing to pre-infection levels at 72 h and increasing again at 7 d post-infection (7 fold).
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