Sentence examples for decrease in turnover rate from inspiring English sources

These mutants show a strong increase of Km and some decrease in turnover rate against MpNPT (Fig. 4a).

Our previous results show that when we used DmTRΔ8 and peptide substrates in which each Cys residue of the dyad is replaced with Sec, there is a 12-fold increase in turnover rate relative to that of peptide I when Cys2 is replaced with Sec (peptide VI), and a 10-fold decrease in turnover rate relative to that of peptide I when Cys1 is replaced with Sec (peptide VII).

The importance of F495 for substrate binding is underlined by significant decreases in turnover rates of the natural substrate MHET and the chromogenic substrate MpNPT by the respective alanine mutant (Fig. 4a, b).

For 1 Hz stretch, the initial drop in time-averaged αavg results in a rapid decrease in SF turnover rate.

Elevated levels of protein carbonyls could be caused by an increase in protein oxidation or by a decrease in the turnover rate for oxidized proteins.

The change in the catalytic efficiency can be mostly attributed to the decrease in the turnover rate, possibly indicating that these residues are required for the correct orientation of the substrate, for stabilization of the tetrahedral intermediate, or for the protonation of the hydrolyzed lactones and therefore do not change the substrate specificity.

This decrease in CSF turnover rate may be one of several clearance pathway alterations that influence age-related accumulation of brain amyloid.

A high-fat diet decreased ATP turnover rate in muscle in rodents (19).

The decreasing CSF turnover rate in older rats suggests a possible therapeutic target to improve CSF solute clearance by shunt insertion in the aging F344/BN rat.

For both local and global population dispersal, using local habitat dynamics always increases population density relative to the case with global habitat dynamics, due to the resulting segregation of habitat turnover, decrease in effective habitat turnover rate, and presence of stable habitat corridors.

In studies, applying indirect measures of protein turnover, in vitro models provide results that suggests that attenuated energy turnover and loss of muscle mass may be developed at hypoxia exposure due to a decrease in overall protein turnover rate [7] [10].