Sentence examples for decrease in the responsiveness from inspiring English sources

The present study was designed to test the hypothesis that a decrease in the responsiveness of somatodendritic 5-HT-1A receptors by the coadministration of buspirone could reverse the induction of VCMs and supersensitivity at 5-HT-1A receptors by haloperidol.

This plasticity can be manifested, for example, as a decrease in the responsiveness of individual neurons in the deprived columns, that is, those representing the trimmed whiskers, or as an increase in responsiveness in nondeprived columns (Fox 1992; Glazewski and Fox 1996; Glazewski et al. 1998).

These data reveal aging-related decreases in the responsiveness of cortical cholinergic afferents, tested under physiologically relevant conditions, to local depolarization and may provide a neuronal mechanism contributing to the cognitive deficits reported in normal aging- and age-related pathological conditions.

In summary, this study found that chronic alcohol intake significantly impedes the ability of opioid peptides to endocytose MOR, which leads to a decrease in the functional responsiveness of MOR and behavioral antinociceptive tolerance.

Intense exercise training accentuated the decrease in the myocardial responsiveness to β-adrenergic stimulation induced by diabetes.

In asthma, the decrease in the cough responsiveness to mannitol is apparent after three months' ICS therapy but continues to decrease up to six months.

The major finding of this study is that intense exercise training accentuated the decrease in the myocardial responsiveness to β-adrenergic stimulation induced by diabetes.

Over-expression of SOCS1 and SOCS3 proteins in melanoma cell lines led to a significant decrease in the IFN-responsiveness of melanoma cells.

Young et al. (1993) and Feske et al. (2000) also found a decrease in lithium responsiveness in the presence of anxiety disorders.

Although normal aging involves a decline in appetite, 124 hyperleptinemia observed in the elderly may serve to counterbalance the decrease in hypothalamic responsiveness found in both animal and human models of aging.

The decrease in cough responsiveness to mannitol associates significantly with the healing of cough [ 11].