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While studies of selection in polyploids are very limited, a recent empirical study in the allotetraploid Capsella bursa-pastoris analyzed about 40% of the genome and showed a decrease in the efficacy of purifying selection in one of the subgenomes but an increase in another subgenome8.
In membranes of CHO-h5-HT1A, 5-HT stimulated guanosine-5′-O- 3-[35S]thio -triphosphate guanosine-5′-O- 3-[35S]thio -triphosphate guanosine-5′-O- 3-[35S]thio -triphosphate guanosine-5′-O- 3-[35S]thio -triphosphate guanosine-5′-O- 3-[35S]thio -triphosphate guanosine-5′-O- 3-[35S]thio -triphosphatet Gαi3.
Decrease in the power correlation coefficient (PCC) between these two signals is meant to describe a decrease in the efficacy of the transmission in the neural circuit.
For low levels of the dhps double mutation, there was a significant decrease in the efficacy of IPTi 35 days post the 9 month dose with increasing frequency of the dhfr triple mutation.
found that no decrease in the efficacy of BTXA after renewed injections 26.
Thus, a decrease in the efficacy of KCC2-dependent hyperpolarizing inhibition is expected to promote triggering of seizures (see Introduction).
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"Efficacy" refers to a decrease in the vaccine efficacy from 85% in the demonstration scenario to 75%.
A decrease in the antiviral efficacy for susceptibility renders the antiviral drug less effective.
We suggested that this is chiefly due not to changes in the numbers of cells initiated by DMBA, but rather to a decrease in the promotional efficacy of TPA in ageing mice.
One of the major contributors to the aging process is mitochondrial dysfunction, which involves a decrease in the oxidative phosphorylation efficacy and an increase in the electron leakage resulting in reduced ATP generation [ 17].
Mutations W206A45.54 and Y311A6.48 also resulted in decreases in the maximal efficacy (Emax) of 45.0 and 53.4%, respectively, for OxA and OxB.
More suggestions(12)
decrease in the appropriateness
decrease in the validity
decrement in the efficacy
decrease in the effect
decrease in the potency
decrease in the impact
decrease in the efficiency
decrease in the efficient
decrease in the therapeutic
decrease in the effective
reductions in the efficacy
decrease in the cost effectiveness
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Justyna Jupowicz-Kozak
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