Sentence examples for decrease in the differentiation from inspiring English sources

Interestingly, we found a decrease in the differentiation of DA precursors into TH+ neurons in Dkk1+/− embryos compared with Wt littermates (Figure 3E).

These changes were in agreement with a dramatic decrease in the differentiation capacity of C2-sh-p53 compared to C2-sh-control cells, as reflected by the formation of multinucleated fibers, and the expression of myosin heavy chain in the fibers (Fig 7C).

Lastly, a strong CEABAC dose-dependent decrease in the differentiation of colonocytes, at least for the goblet cell lineage in the crypts, was observed in the transgenic mice (Figure 5), consistent with the pan-inhibition of cellular differentiation noted in various in vitro systems [9] [11].

Aging affects the bone marrow microenvironment in multiple ways, including a decrease in the differentiation potential of cells associated with decrease in bone formation.

In this regard, use of our system showed that a lower temperature led to a decrease in the differentiation rate, as previously shown in the salmon [ 7].

These observations have led us to conclude that temperature increase is more relevant than pH decrease in the differentiation process to the amastigote stage with regard to transcriptome variation in L. infantum.

The specific influence of temperature and pH on the differential regulation of genes described in this study and the evidence provided by clustering analysis is consistent with the predominant role of temperature increase over extracellular pH decrease in the amastigote differentiation process, which provides new insights into Leishmania physiology.

Conversely, gain-of-function (GOF) experiments with JAG2 (GOF-JAG2) resulted in the decrease in MN differentiation and the percentage of Islet1+/BrdU− decreased to 33±0.02% (∼1.5-fold decrease; Figures 2e and f).

We showed that the Npm1/Sox2 complex was sustained when cells were induced to differentiate by retinoic acid, while decreased in the other differentiation pathways.

The positive expression rate of HE4 increased with a decrease in the degree of differentiation.

With a decrease in the degree of differentiation, the HE4 positive expression rate increased, and HE4 expression in the poorly differentiated group was significantly higher than that in the highly differentiated group (Phigh:low = 0.024, Phigh:middle = 0.348, and Pmiddle:low = 0.254).