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And the researchers have tied the decrease in survival to rising winter temperatures.
Relative to the compatible genotypes, (simw ); OreR experienced a 28% and a 38% decrease in survival to pupation at 22° and 25°, respectively.
In fact, a recent multicenter study found an 18% decrease in survival to hospital discharge for every 5 s increase in preshock pause length [ 19].
Actually, clinical studies have also confirmed that longer pauses in CC before and after defibrillator shocks were independently associated with a decrease in survival to hospital discharge [ 6, 7].
Exposing late third-instar larvae to radiation results in a dose-dependent decrease in survival to eclosion, shortened adult lifespan, impaired locomotion and increased cell death in the adult brain.
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This result is expected for the family-size variance, whereas decrease in survival seems to increase family-size variance and thus to lower generational Ne value.
In the LM2-4LUC+ breast cell model, preconditioning mice with XRT, MTD CTX, and sunitinib lead to significant increases in metastasis and a decrease in survival compared to control (Fig 4A), as has been previously shown (Ebos et al, 2009; Ebos & Kerbel, 2011).
On average, an elo null mutation produced a 40% decrease in survival compared to wild-type.
Aged elo2Δ and elo3Δ mutants exhibited a modest, but significant, decrease in survival compared to aged wild-type cells, although neither mutant accumulated significant levels of ROS (Figs. 3, 4).
However, there was no difference in tumor-free survival and tumor growth between 12-month-old resveratrol (PD-RES) fed mice and control diet (PD) fed mice, with both 12-month-old groups experiencing a dramatic decrease in survival compared to the αOX40-treated 2-month-old mice (Fig. 3e, f).
Subsequent analyses performed with CalcuSyn demonstrated that administration of AMG 900 (1 nmol/L) combined with VPA (1 mmol/L and 1.5 mmol/L) resulted in a strongly synergistic decrease in survival compared to the single compounds in DU-145 and PC3 cells (0.171 < CI < 0.260) (Fig. 2C, Table S1) 22, 22.
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