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This decrease in specificity was attributed to the non-specific nature of visual detection, and the increase in non-targeted DNA from the sample preparation technique.
As compared to individual tools, DIOPT shows increased sensitivity with only a modest decrease in specificity.
The increase in sensitivity seen in the DipEx group was accompanied by a significant decrease in specificity compared with the Dip group (67% vs 100%, P =.000001).
It exhibits the tradeoff between "sensitivity" and "specificity" i.e. an increase in "sensitivity" will be accompanied by a decrease in "specificity".
Adding SWAP to each of the best structural parameters led to a significant increase in sensitivity and also a significant decrease in specificity compared with each structural parameter alone.A combination of parameters from structural tests and functional tests can improve the sensitivity of glaucoma detection.
After threshold relaxation, there was a small decrease in specificity, but a much larger increase in sensitivity.
Therefore, only a very small decrease in specificity from 1 can result in the same bias as a high decrease in sensitivity.
However, this could possibly lead to a decrease in specificity as the surveillance system could potentially falsely signal when there was an increase in other causes of influenza-associated hospitalisations, e.g. respiratory syncytial virus.
The results shown in Figure 3 demonstrate that in contrast to the typically observed decrease in Specificity with decreasing numbers of replicates (not shown) we observed no decrease in Precision as the number of replicates was reduced.
Lack of sequence conservation partly explained the decrease in specificity.
However, this is associated with a clear decrease in specificity and accuracy.
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CEO of Professional Science Editing for Scientists @ prosciediting.com