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The present study confirmed an age-dependent GH and IGF-1 decrease in rats of both strains.
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The decrease occurred in rats of both ages and was independent of the healing status of the fractures.
Age-related body weight gain followed by its decrease was observed in rats of all groups at any light/dark regimens.
We cannot, however, rule out the possibility that RNA editing levels may decrease in rats after the age of 28 months.
Previously, stool-related factors such as pellet number, weight, and water content were shown to be dramatically decreased in rats upon administration of Lop [ 6, 10, 11, 29].
However, p-CREB binding was decreased in the rats of EA group.
VLDL and LDL cholesterol levels were significantly decreased in rats fed the water extract of Puerariae radix.
In contrast, the two METH challenges caused decreases in rat body weights independent of the type of pretreatment (−8.4% for SMM group and −7.5% for MMM group) (Fig. 1).
KGF has been shown to prevent lung injury and decrease mortality in rat models of ALI, suggesting a possible therapeutic use.
Previous publications indicate that LPS alone would not cause cell death, but LPS combined with cytokines, i.g., interferon-γ (INF-γ) would cause decrease in viability of rat C6 and rat primary astrocytes [ 20, 21].
For example, Poli et al. (1990) have demonstrated decreased neurotoxicity in rats upon slow infusion of brevetoxin 3 by injection compared with administration of a bolus dose.
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