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The study was cautious in its language, warning, "A causal relationship cannot be inferred between the fitness interventions implemented by New York City in schools and the decrease in prevalence of child obesity described in this report".
The cause for this decrease in prevalence of polymicrobial infection is uncertain.
Quantitative analysis showed a decrease in prevalence of alveolar osteitis (odds ratio 0.31, 95% confidence interval 0.13 0.77, Z = 2.54, P = 0.01).
The only significant reduction in overall prevalence was found in the study done in the UK, powered and designed explicitly from its outset to detect change across generations (decrease in prevalence of 22%; p=0·003).
Another potential explanation is that a decrease in ALT signifies a true decrease in prevalence of liver disease.
The fitness assays showed that the T186S mutation in TL9 was associated with a fitness cost (P<0.0001) and it is therefore possible that in patients with B*8101 and low CD4 counts, the decrease in prevalence of the T186S mutation reflects reversion to a fitter strain coincident with the weakening of T cell responses.
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These changes were associated with concomitant decreases in prevalence of maternal anemia and LBW, important indicators of maternal malaria morbidity.
Recent evidence regarding temporal trends of asthma burden has not been consistent, with some countries reporting decreases in prevalence of asthma.
For instance, decreases in prevalence of smoking in men caused the decline of lung cancer incidence and mortality, and partially a decline in bladder, kidney, and larynx cancer [ 17, 18].
In contrast to the decreasing trend in prevalence of TB during the study period, the annual incidence of pulmonary NTM disease and colonization increased significantly over time (p<0.01).
This retrospective cohort study identified a 41% decrease in prevalence density of all SAB in an inpatient population from Scotland between 2006 and 2010.
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