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Covariates were considered for inclusion in the model if they were biologically plausible and there was improvement in the base model, that is, decrease in objective function (at least 3.84 units), decrease in the unexplained between-subject variability of the parameter, or decrease in residual unexplained variability.
A small but significant number of subjects reported decreased tinnitus annoyance that corresponded with a decrease in objective measures of tinnitus loudness during active drug treatment with a washout effect during placebo treatment.
The reduction of out-of-hours shifts is thus associated with both a decrease in objective and subjective workload.
For the inclusion of fixed and random model parameters as well as covariates, a decrease in objective function corresponding to p < 0.01 was considered to be statistically significant assuming a χ distribution.
If more than one significant covariate was found, the covariate model causing the largest decrease in objective function was chosen as a basis to explore the influence of additional covariates sequentially with the use of the same criteria.
The analysis showed that TBW was the most predictive covariate for propofol clearance when implemented using an allometric function (model B, decrease in objective function value (OFV) of 84.4 points; P < 0.001; Table 2 ). Figure 1 model B (and model A) shows that adolescents with the same TBW as adults had lower clearance values (gray vs. black symbols, respectively).
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Results show that an increase in the tube number leads to decrease in the objective function first then it leads to a considerable increment in objective function.
Unexpectedly, memory strategy training was associated with decreases in objective memory performance at three [ 28] and six months [ 36] post training compared to control.
The influence of oestradiol levels or progesterone levels on glucuronidation clearance - implemented as a power function - resulted in decreases in objective function of 60.5 points and 68.9 points respectively.
For secondary research questions including whether the Walks4work programme can increase general physical activity, fitness levels, HRR from stressor and exercise test and also lead to decreases in objective and perceived markers of stress again mixed ANOVA will be used.
Decrease in milk production.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com