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If so, the localization of the effect in this region with an accompanying decrease in motivational responding indicates that the effect of GSK1521498 is to disrupt motivational responding to food or "food seeking" in the absence of actual reward consumption.
A general mechanism of a decrease in motivational responding to food cues might suggest that both the dot probe and Stroop food-cue tasks might be similarly affected; alternatively, MOR antagonism might have a specific influence by improving inhibitory mechanisms to food cues.
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We show that loss of motivational drive in CRS-exposed animals in the saccharin preference test can transfer to a decrease in motivation for an alternative appetitive stimulus.
For all of the players, the estimated values of the motivational model 5 (initial motivation, decrease of motivation, motivational increment and decrement due to the opening of an empty chest) did not differ significantly in different environments (respectively. F = 0.13, df = 4; 71, NS, F = 1.01, df = 4; 71, NS, F = 0.66, df = 4; 71, NS and F = 1.93, df = 4,71, NS).
Across healthy participants, those who had the greatest increase in velocity also had the greatest decrease in motor variability, indicating stronger motivational effects (r = 0.23, p = 0.001; Figure S4A).
However, we observed a significant decrease in interest for estrous urine, suggesting that these animals exhibit deficits in motivational drive.
I use that story in motivational speeches.
Today most are seeking careers in motivational speaking.
There are corresponding differences in motivational states.
The redesign was grounded in motivational research.
The investment in motivational training is a little less conventional.
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CEO of Professional Science Editing for Scientists @ prosciediting.com