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Vaccinated rats showed a 45% decrease in locomotor activity compared to a 16% decrease in controls.
Increase in locomotor effect is considered as an increase in alertness and decrease in locomotor activity indicated sedative effect [36].
Catechin administration attenuated the increase in rotational behavior and the decrease in locomotor activity observed in lesioned rats.
Passive immunization with NIC9D9 resulted in a 66.9% decrease in locomotor activity versus a 3.4% decrease in controls.
Acute immobilization stress resulted in decrease in locomotor activity, frequency of head dips and rearings in hole board; line crossing and rearing in the open field; increase in avoidance in social behavior along with development of memory deficits assessed by an increased transfer latency time and elevation of the corticosterone levels.
Aged rats have an inherent decrease in locomotor activity and provide intact neuropil to compare where DA bioavailability affects locomotor activity measures.
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Time-dependent measurements in CLP-induced septic animals were in accordance with previous reports in terms of decreases in locomotor activity and increases in depressive-like behavior [8].
Males with either silenced or ablated corazonin neurons show a diminution of stress-induced activity for starvation and osmotic stress, and are resistant to the decreases in locomotor activity caused by oxidative stress (Figure 4B).
Similarly, addition of resveratrol postponed age-related decreases in locomotor activity of short-lived vertebrate fish, N. furzeri [ 18].
Time-dependent measurements in CLP-induced septic animals were in accordance with previous reports in terms of decreases in locomotor activity and increases in depressive-like behavior [ 8].
However, it induced dramatically an initial decrease and then an increase in locomotor activity in rats [ 1, 8].
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