Within the PVN, decreases in BBB integrity might have effects amplified by the threefold greater vascular network (Goldstein et al. 2013).
A 2.6-fold decrease in oocyst integrity was observed over the first 24 h of incubation (38.05 % integrity), and integrity further decreased by 2-fold between 24 and 48 h (18.90 % integrity) (Fig. 4).
Ratios of mtDNA/nDNA were used to obtain the relative DNA integrity whereby a lower ratio represents less initial template, denoting a decrease in the integrity of mtDNA.
A chronic increase in HIF-2α leads to high turnover of the tight junction protein occludin, leading to a decrease in barrier integrity [17].
Results show that there is an alarming decrease in structural integrity and durability functions in abandoned reinforced concrete buildings with time.
This finding may suggest that the decrease in axonal integrity originates from the cell body, which is in accordance with the observed cortical thinning.
Together, these data indicate alterations in blood vessels and a decrease in BBB integrity in G3 mTerc−/− mouse brains.
The decrease in acrosome integrity might thus be due to acrosome reaction in addition to membrane damage.
The decrease in acrosome integrity from one storage time to the next was highly significant throughout the trial (p < 0.001).
Slides were also stored at -80°C for eight days with no decrease in RNA integrity (data not shown).
