Sentence examples for decrease in fidelity from inspiring English sources

"There is a decrease in fidelity".

Moreover, several examples exist of point mutations in Polβ causing a dramatic decrease in fidelity [27] [32].

The modest decrease in fidelity in unlikely to provide a number of defectors genomes sufficient to outweigh the decrease of defector genomes due to R-mediated mutagenesis during replication of the mutant virus.

To rule out a decrease in fidelity of this enzyme induced by the proprietary modification, we performed polymerase fidelity assays (Flaman et al, 1994).

The role of mRNA translation is not well defined but an overall increase in translation could cause a decrease in fidelity of protein synthesis, increasing the overall burden of misfolded proteins hence contributing to oxidative stress (Kapahi et al, 2010).

The metal ion-dependent decrease in fidelity for 8-oxo-dG bypass (3.2-fold) is slightly greater than the metal ion-dependent change in fidelity observed for undamaged template DNA (1.7-fold).

However, like PrimPol, hpol ι shows modest decreases in fidelity in the presence of Mn2+.

However, in cases where what is transmitted is only partially presented, very complex, or the channel is noisy, then there is a decrease in the fidelity of what is transmitted across iterations just like there is in the children's game of Telephone.

In fact, a modest decrease in copying fidelity was observed.

It has been shown that a decrease in the fidelity of a particular DNA polymerase can lead to detrimental cellular effects, including cell death, cancer, and other genetic diseases [25], [26].

RNA viruses are well known to accumulate mutations at a very high rate [45], which on one hand, allows them to quickly adapt to variations in environmental pressures [46], [47], but on the other hand, renders them susceptible to a very subtle decrease in RdRp fidelity, which can force a virus into error catastrophe [48], [49].