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To reach recovery not only a decrease in fatigue severity is important, it is also important that a change in the evaluation of fatigue in the patient occurs.
Across acute-phase treatment groups, patient global impression of feeling at least 'much better' was associated with a 2- to 3-point decrease in fatigue severity across MFI domains, suggesting that improvement in fatigue may be as important as improvement in pain in this patient population.
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Patients in the intervention condition reported a clinically relevant decrease compared to patients in the waiting list condition in fatigue severity, functional impairment and psychological distress.
Patients treated with paroxetine reported less depressive symptoms at follow-up; however, no differences in fatigue severity were observed.
Only in the subset of four patients with severe fatigue a decrease in fatigue was observed [ 16].
When a decrease is seen in the fatigue severity of a patient and the evaluation of the fatigue stays negative, it implicates that a patients still suffers and is disabled due to the fatigue.
Furthermore, the yoga group had a 24percentt decrease in pain, 30percentt decrease in fatigue and 42percentt decrease in depression.
Increase in HR-QoL was associated with decrease in fatigue.
We found decreased fatigue severity scores at the 1-year follow-up, but these levels were still significantly higher than values for normal fatigued controls [ 9]; thus, from a practical standpoint, subjects remained severely fatigue throughout the follow-up period.
6– 9 Others have demonstrated an improvement in the fatigue severity scale and a decrease in the Expanded Disability Status Scale (EDSS).
However, patients receiving pemoline did not differ from patients who received placebo in reported fatigue severity.
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