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The results showed that the decrease in brain volume was greater among those with lower vitamin B12 levels.
Earlier this year, a study from researchers from New York University's Langone School of Medicine showed that a single concussion could prompt a decrease in brain volume.
This is of the highest importance, because SLE patients show long term neurological damage, which manifests itself as a decrease in brain volume and a worsening of cognitive function [33], [34].
The mean decrease in brain volume from +2 to +5 years was 4.4% (S.D.=5.9%, p=.06).
Schizophrenic patients exhibit overall a decrease in brain volume in the temporal and frontal regions [ 42, 43].
A decrease in brain volume has been described previously with high-dose cytotoxic therapies for patients with hematological malignancies.
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Therefore, the main finding of this largest longitudinal study investigating brain volumes in schizophrenia patients is that the relationship between antipsychotic treatment and decrease in brain volumes in schizophrenia patients over time remains significant, even after correction for alcohol/illicit drug misuse and for illness severity/duration [ 24], [ 30].
Friedman and colleagues studied cohorts of adolescents with schizophrenia and bipolar disorder compared to controls, and found evidence of decreases in brain volume when both patient groups were compared to controls, but the patient groups did not differ from each other [ 24].
The decreases in brain volumes correlated well with the poor performances of the infected patients in the neuropsychological tests [ 42].
Harrison in a 1999 review of the neuropathology of schizophrenia comments that despite over a hundred years of research on the topic, specifics remain obscure, with studies using meta-analyses most often supporting evidence of increased ventricular volume and selected decreases (cortex and hippocampus) in brain volume [ 17].
This decline in brain volume is consistent with autopsy studies showing that brain weight decreases after age 40 years.
More suggestions(17)
decrease in brain function
decrease in tumor volume
decrease in clearance volume
decrease in brain wave
decrease in pore volume
decrease in bone volume
decrease in brain Aβ
decrease in brain death
decrease in brain PtO2
decrease in brain weight/body
decrease in blood volume
decrease in brain blood
decrease in infarct volume
decrease in brain oxygenation
decrease in production volume
decrease in tree volume
decrease in brain glutamate
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