Sentence examples for decoupling agent from inspiring English sources

However, using the cellular bioenergetics assay, we found that there was a significant difference in maximal respiration levels in RS63-3 and -7 compared with WT levels when the respiratory chain decoupling agent, FCCP, was added to cells.

To illustrate the effectiveness of the approach, a study of the T47D cell line mitochondrial membrane potential as a function of the CCCP decoupling agent concentration is performed.

Notably, however, the drug effects showed disparate and appeared to be related with the target of the molecules; thus, treatments with Complex I and II inhibitors (Deguelin and Atpenin, respectively) resulted in a noticeable increase in the intracellular SO level while treatments with a Complex V inhibitor (Oligomycin) and a H+ decoupling agent (FCCP) resulted in a slight decrease in the SO level.

To determine the implication of mitochondria in β-cell development, we used the mitochondrial decoupling agent CCCP.

The mitochondrial spheroid formation process illustrated in Ding et al., also using a mouse embryonic fibroblast cell line, indicated that the "mitochondrial spheroid" formation induced by the mitochondrial decoupling agent CCCP, is dependent on mitofusin-1 and mitofusin-2.

Those results prompted us to examine other mitochondrial antagonists with distinct mechanisms of action; Piericidin (a Complex I inhibitor) [18], Atpenin (a Complex II inhibitor) [19], Oligomycin (a Complex V inhibitor) [20] and FCCP (an H+ decoupling agent) [21].

In both scenarios, we establish sufficient conditions guaranteeing global exponential decoupling of agents.

They found a way to establish suitable decoupling of agents and shipments and determined transport demand elasticities with respect to monetary cost and travel time.

The main challenge lies in retaining the recoiled alpha-emitting daughter nuclides, which are decoupled from targeting agents upon emission of an alpha particle and can subsequently cause unwanted toxicity to healthy tissue.

Moreover, the transient and steady state response is solely determined by certain designer-specified performance functions and is fully decoupled by the agents' dynamic model, the control gain selection, the underlying graph topology as well as the initial conditions.

However, DNA damaging agents (e.g., etoposide) cause the transcription factor to accumulate within cells by decoupling this degradation.