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Unlike the uniform negative slope of the size distribution of variants annotated in the Sanger-based HuRef Standard, there were notable declines in sensitivity in the CG version, particularly for gains in the paired-end detection range, which spanned from 100 bp to 10 kb.
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The upper limits of the linear ranges (determined as 5% decline in sensitivity) for five commercial detectors ranged from 0.175 to 1.2 AU.
In the present example, the air-saturated, baseline-corrected O2 current decreased from 34.1 nA to 16.9 nA after four days, a 50% decline in sensitivity.
There was a small gradual decline in sensitivity across blocks; however, none of the post-hoc pairwise differences were significant (M diffs < 0.2, P > 0.05).
However, each 10-μm greater RPEDC layer thickness and 1-HF present was not independently associated with a further decline in sensitivity (-0.08 dB/year, 95% CI = -0.24 to 0.07 dB/year, P = 0.288 and 0.09 dB/year, 95% CI = -0.06 to 0.24 dB/year, P = 0.242, respectively) over time when accounting for the association between RPEDC layer thickness and number of HF with microperimetric sensitivity.
Loss of accuracy in tasks involving complex visual information can result from either a decline in sensitivity or a change in response bias [36]; with a decline in d' we can infer a loss of sensitivity.
More notably, this decline in sensitivity (confirmed by a t-test) was most pronounced on the first night shift in the more difficult spatial configuration search task (Figure 2, lower right panel).
Saturated decline in sensitivity often leads to logarithmic scaling.
The decline in sensitivity to collagenolytic enzymes appears to be a highly programmed event.
However, when the radius increased to 3 km, the decline in sensitivity was greater (51%).
In regard to ATP, there was a clear decline in sensitivity only in the group with more developed endothelial dysfunction.
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