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The immunodensities of GRK2 (r=−0.71), GRK6 (r=−0.61), and β-arrestin-2 (r=−0.54) in human brain (n=12) also declined with aging (16 to 87 years) and the average decreases per decade (from 20 to 80 years) were 3 5%.
The levels of NEP are declined with aging and hypoxic condition, two of the high risk factors for AD [5], [6].
In another recent study, locomotion declined with aging in Drosophila although males performed better than females at advanced age (Simon et al. 2006).
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However, thermoregulatory function is thought to decline with aging.
In line with this notion, proteostasis has been shown to decline with aging [66].
Spatial orientation is an essential ability, which has shown to decline with aging.
Mean blood concentrations of hemoglobin progressively decline with aging [1].
Does prospective memory with focal vs. non-focal cues decline with aging?
Hormone concentrations decline with aging.
Mitochondrial respiratory capacity declines with aging.
Dermal cellular adenosine triphosphate (ATP) levels decline with aging.
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CEO of Professional Science Editing for Scientists @ prosciediting.com