Sentence examples for declined expression of from inspiring English sources

7. NotI microarrays and qPCR on genomic DNA we tested for possible mechanisms of the declined expression of RBSP3 in NSCLC.

IFN- γ treatment declined expression of LXR- α by 34.6 ± 3.2% versus control), TNF- α downregulated mRNA and protein level of LXR- α to 41.2 ± 2.5% and 53.2 ± 8.7% (P < 0.01, n = 3), respectively.

This was proved by a study that showed lowered activation of sympathetic nerve and declined expression of UCP-1 in BAT of obese rats and by another in vivo study that reported overexpression of UCP-1 reduced degree of obesity induced by high fat diet.

During the development of obesity, adipose tissue undergoes a switch from being mainly a metabolic organ towards an organ that shows substantial pro-inflammatory activity, associated with decreased insulin sensitivity, declined expression of adiponectin and enhanced production of pro-inflammatory cytokines and chemokines.

Declined expression of RBSP3 and NPRL2 was observed in 61% of samples (P < 0.05), RBSP3 and RASSF1A in 50% (P < 0.05), and NPRL2 and RASSF1A in 44% (P < 0.05) of cases.

This study also found markedly declined expressions of the eight genes related to cell proliferation and differentiation.

Declining expression of HMGA2 during adulthood allows the expression of these gene products to increase during aging.

We also observed progressive loss of nuclear PQM-1 during wild-type aging, along with declining expression of its target genes.

It is noteworthy that in sepsis neutrophils often fail to move to the infectious site because their chemotaxis is reduced by declining expression of CXCR2, an essential chemotaxis receptor, but A2MG prevented this decline.

The declining expression of oxidative phosphorylation genes in monocytes is consistent with previous findings across species [ 50- 53], and from previous transcriptomic studies of aging in human muscle [ 7, 9], and brain [ 7] tissues.

Unlike CD4-dependent TCR signalling, which is disrupted during MHCII-specific positive selection in 4in8 mice by declining expression of Cd8-encoded CD4 coreceptor proteins, CD4-independent MHCII-specific TCR signalling persists throughout positive selection.