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The concentration of testosterone in blood samples declined age-dependently from 12.9 nM (IQR = 4.5 nM) to 10.8 nM (IQR = 4.9 nM) (Fig. 1E).
In settings where early marriage prevails, however, declining age at menarche could increase lifetime fertility.
Declining age at menarche has been observed in many countries.
Improvements in socioeconomic conditions and population health have been linked to declining age at menarche.
Our data suggest a trend of declining age of menarche in Nigerian girls.
The present study is the first to demonstrate the trend of declining age at menarche in Chinese ethnic minority girls.
Declining age-specific incidence may also play a role.
Declining ages of pubertal onset associate with increased BMI in childhood (4– 7).
With more slowly declining age-specific incidence, higher false negative measurement rates provide a better description of the observed pattern.
Both absenteeism and presenteeism rates declined after age 34 years (P <0.0005).
People aged 75-79 also reported high levels of satisfaction with life, although this declined with age.
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