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Sheen, Y. J. & Sheu, W. H. Risks of rapid decline renal function in patients with type 2 diabetes.
Copeptin is a surrogate marker of arginine vasopressin (AVP) system and is proposed as a biomarker of decline renal function.
Our results complement Song et al.'s finding as we further demonstrate an independent inverse relationship between Lp(a) concentration and decline renal function in diabetics without baseline CKD, suggesting that Lp(a) is not only involved in progression of renal disease but also possibly the development of GFR impairment.
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The treatment activity for the intervention arm was selected on the basis of histological examination and declining renal function.
CONCLUSIONS AND RELEVANCE In patients with atrial fibrillation, declining renal function was more common in elderly patients and those with cardiovascular comorbidities.
No cases of severe or end-stage renal failure were encountered, probably owing to close clinical monitoring and timely interventions in cases with declining renal function.
Other findings implicate episodes of acute lithium intoxication (possibly an indication of more aggressive treatment) with declining renal function (Rej et al. 2012).
Operative mortality rose inversely with declining renal function, from 1.3% for those with normal renal function to 9.3% for patients with severe RD not on dialysis and 9.0% for those who were dialysis dependent.
Reducing lithium dose might be expected to limit toxic effects as was supported by present findings (Tables 4, 5, assuming that dose was not lowered because of declining renal function).
59 As expected, clearance of avibactam declined with declining renal function.
DMN is characterised by declining renal function and ultimately end-stage renal disease.
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