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The total cell expansion was associated with a gradual decline of the frequency of CD34+ cells from 84% ±16%at day 0 till 47%±14% at week 1 and 17%±9% at week 2 (Figure S1a and S1b).
The proportion of damp housing conditions had partially increased until 1996 in East Germany, but thereafter, reconstruction measures of homes around that time might be responsible for the slight decline of the frequency of damp housing conditions.
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The transformation frequency declined with an extended pre-culture time, with a 6-day pre-culture resulting in a decline of the transformation frequency to 51.11%.
The rate of decline of the median frequency for different trunk muscles were different (p<0.01).
A sharp decline of the transcript frequency is displayed at a distance >3 kb.
The decline of the mutation frequency in time that is observed in this study, however, could indicate the presence of genotoxic effect.
Grant et al. (1995, 1996) stress the similarity in the pattern of decline in the frequency of the respective forms on the Wirral in England and at the George Reserve, 30 miles west of Detroit.
In adults, the circulating B cell pool is maintained by output of cells from bone marrow and division of lymphocytes in the periphery, with the relative contribution of the two processes not well understood 37. Thus, one likely cause of the decline in the frequency of total B lymphocytes with age is a decreased bone marrow output.
In a second study the same authors did not find a decline in the frequency of aggression in spite of a reduction of the number of beds by 50% [ 32].
Although intrachromosomal duplicates dominate in frequency within each of the three age-cohorts, a clear decline in the frequency of intrachromosomal duplicates (and increase in the frequency of interchromosomal duplicates) is apparent as a function of increasing synonymous divergence: 100 (39/39), 88 (65/74), and 66%% (39/59) from evolutionarily younger to older age-cohorts (Fig. 2).
He cites, as an example of recent evolution, the steep decline in the frequency of the gene for sickle-cell anemia among African-Americans, compared with what you'd expect to find, given the percentage of their African ancestry and the prevalence of the gene in Africa.
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CEO of Professional Science Editing for Scientists @ prosciediting.com