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We reviewed the evidence on the usefulness of CGA for assessing health problems and predicting cancer treatment outcomes, functional decline, morbidity, and mortality in older patients with solid malignancies.
Aging is a gradual process of morphologic and physiologic changes that naturally predisposes older adults to progressive weakening, functional decline, morbidity, disability, poor quality of life, and increased mortality.
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Combination antiretroviral therapy (cART) has led to declining morbidity and mortality in resource-poor settings [ 1, 2], and scale-up at the end of 2012 had reached 9.7 million human immunodeficiency virus (HIV infected individuals worldwide [ 3].
Analysis of the toxigenicity characteristics amongst the various C. diphtheriae ribotypes demonstrated that despite a dramatic decrease in the circulation of toxigenic strains during the period of declining morbidity, the C. diphtheriae ribotypes that predominated were still toxigenic.
Their use has resulted in a dramatic decline in morbidity (illness) and mortality (death) associated with viral infections such as polio, measles, mumps and rubella.
The advent of potent antiretroviral therapies (ART) a decade ago has led to a substantial decline of morbidity and mortality in HIV infected patients [1] [3].
The decline in morbidity is not as strong as the decline in mortality across time.
Unless treated properly, it is generally progressive with functional decline, significant morbidity, premature mortality, and socioeconomic costs [ 1].
With increased access to highly active antiretroviral therapy (HAART), there has been a dramatic decline in morbidity and mortality from HIV disease [ 4].
According to the World Health organization [ 1] malaria cases are presently coming down in Bangladesh though the rate of decline in morbidity could be improved.
The most likely explanation for this trend is improved glycemic therapy and antihypertensive therapy management with a resulting decline in morbidity.
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