Sentence examples for decline in the function of from inspiring English sources

This may be due to a direct effect of superoxide on a signaling pathway between the nucleus and mitochondria, or may result from a decline in the function of oxidant sensitive components of the electron transport chain (such as Fe S containing proteins)—resulting in a metabolic imbalance that triggers mitochondrial-to-nuclear communication.

A gradual decline in the function of the HPG axis is considered a key element in the development of menopause [ 27, 28].

These studies appear to support the idea of a general age-related decline in the function of feedback prejunctional α2-adrenoceptors.

Although the proportion of residents showing a decline in the function of eating (a late-loss ADL) was high for both groups, it was highest for those with severe impairment (29% moderate vs. 38% severe).

The study was not designed to observe the effects of tobacco smoking in asthma; the separate analysis of non-smokers was intended to describe the decline in the function of asthmatics unencumbered by the effects of cigarette smoking.

In the mitochondrial theory of aging, an age-related decline in the function of the respiratory chain causes increasing ROS, with subsequent accumulation of mtDNA mutations (reviewed in Wallace, 2005).

This increased risk of pain in aging appears to be compounded by age-related declines in the function of endogenous pain inhibitory systems [ 3– 5].

Shared risk factors might become more common with increasing age, such as chronic diseases, dysregulation of homeostasis, and concurrent declines in the function of multiple physiological systems.

Former Israeli prime minister Ariel Sharon, who has been in a coma for eight years, was in a critical condition on Thursday, clinging to life after a decline in the functioning of various bodily organs, his doctors said.

To measure MDI, we modified the approach of Herndon et al.[ 69] to provide a population-level measure of the gradual decline in the muscle function of the same group of animals over time.

CADO treatment inhibited the progressive decline in the contractile function of remote areas and enhanced the contractile function within the border zone.