Exact(1)
One of the major challenges for the damage accumulation theories of ageing is to explain if and how a moderate, linear accumulation of damage with age can cause the rapid decline in systems performance and the exponential increases in morbidity and mortality seen during ageing [8], [57].
Similar(59)
Aging is thought of as a time-dependent decline in system functioning, putting the organism at increased risk of death and disease [ 13].
Lung cancer is considered an age-associated disease, whose progression is in part due to accumulation of genomic instability as well as age-related decline in system integrity and function.
Additionally, there is also a quantitative relationship of latitude with the distribution of scleractinian species, whereby species richness declines in systems that are further south (Veron 1995); this may be due to a lack of connectivity or to changes in habitat suitability for non-generalist species.
Cole's study also found a decline in the systems that defend against viruses.
It appears that eutrophication can result in severe seagrass decline in these systems.
In the heart, the age-associated decline in cardioprotective systems additionally contributes to the development of heart failure (Strait & Lakatta, 2012).
As you spread the VRE across an area, there is a marked decline in the system-wide variability.
HP's Itanium system sales were at an annual rate of $4.4Bn at the end of 2008, and declined to $3.5Bn by the end of 2009, compared to a 35% decline in UNIX system revenue for Sun and an 11% drop for IBM, with an x86-64 serevenuevenue increase of 14% during this period.
Immunosenescence is a result of progressive decline in immune system function with advancing age.
Immunosenescence is a result of progressive and gradual decline in immune system function with advancing age.
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