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30, 31 Alogliptin is primarily eliminated renally, with exposure increasing incrementally with a decline in renal function.
A meta-analysis of the effects of dietary protein restriction on the rate of decline in renal function.
Acute kidney injury (AKI) is characterized clinically as an abrupt decline in renal function marked by reduced excretion of waste products, disordered electrolytes, and disrupted fluid homeostasis.
This decline in renal function can become irreversible and may lead to renal failure (Gitlin 2016).
Most patients develop a progressive decline in renal function, and about 40%% present end-stage renal failure [6].
Newly developed hypochloremia at day 14 was common and associated with a decline in renal function and an increase in blood urea nitrogen (P<0.01).
This hyperfiltration might lead to steeper decline in renal function over time, especially in the presence of renal disease.
Foscarnet is associated with a decline in renal function.
Second, for estimating the rate of decline in renal function, we assumed that the decline in renal function is linear in advanced CKD stages.
The progressive formation and enlargement of renal cysts causes the decline in renal function.
This decline in renal function was reversible and probably reflects a fall in glomerular pressure.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com