Sentence examples for decline in organ function from inspiring English sources

The cumulative molecular and cellular changes which are characteristic of mammalian aging result in the widespread decline in organ function and the inevitable death of the organism.

Another hallmark of aging is the body's loss of its ability to make new cells when old ones die, causing a progressive decline in organ function with age.

When loss exceeds replacement, it will lead to a decline in organ function and ultimately organ failure.

The progressive decline in organ function in these diseases is pronounced and unrelenting, due, in part, to the lack of effective treatments being available.

As aging is associated with progressive decline in organ function, elucidating the complex pathways controlling the rate of aging is of significant clinical importance [1].

In addition, individual doses in elderly patients cause different degrees of decline in organ function.

There is a decline in organ functions progressively along with the age-related disease development.

The effects of these declines in organ function on the pharmacokinetics of therapeutic drugs and toxicants are discussed in more detail below.

Age-related disruptions in cellular homoeostasis result in declines in organ functions and in the responsiveness to physiological stress.

In septic patients, the most recent in-depth analysis demonstrated that MODS is often a key contributor to mortality but not through a rapid and overt failure but rather through a protracted process of the gradual decline in the organ function [5].

Although aging is associated with a decline in organ system function, Wasserman has pointed out that we all age physiologically at different rates.