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After a 24-h exposure, a 25% decline in cell viability was observed in Vero cells exposed to 50 μg/ml of 10-nm uncoated Ag-NPs (Figure 1).
To rule out the possibility that the reduction in cytokine production by these peptides was related to peptide-induced decline in cell viability, the cell survival was measured after six hours of LPS-stimulation.
A silver nanoparticle dose-dependent decline in cell viability of consortium and individual isolates was compared under UVC and dark conditions to evaluate the antibacterial activity of the nanocomposite.
However, PS exposure could not be identified to the same extent on rBHK-21host cells despite a similar decline in cell viability between rBHK-21host and BHK-21native batch cultures.
In the conventional Photosan group, cells incubated for 2 h in the presence of 5 mg/L photosensitizer showed a gradual decline in cell viability as light doses increased from 2.5 to 10 J/cm2, with significant differences at different light doses.
When compared to free RV and HRP NPs, HRP RGD NPs can result in greatest decline in cell viability under all test concentrations, likely due to the stability and RGD targeting effects of HRP RGD NPs to PANC-1 cells [30, 31].
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In the present study, in vitro test results show that ZnO NPs imposed distinct toxic effect on LTEP-a-2 cells, and the declines in cell viability and survival rate coincided with specific morphological changes and the occurrence of apoptosis.
The sharp decline in cytokine expression at doses exceeding 5 μM HNE cannot be explained by a loss in cell viability.
In contrast to the breast cancer cells, MCF10A cells demonstrated no reduction in cell viability from As2O3 treatments at or below 2.5 μM, although viability significantly declined at higher concentrations.
Similar to D283 and trans-hENs, reduction of OTX2 resulted in a significant decline in self-renewal capacity (supplementary material Fig. S7B-E); however, for this cell line, a significant decrease in cell viability was observed (supplementary material Fig. S7D).
These cells also differed in cell viability and proliferation ability.
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