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This paper presents an exploration of the reasons why breast cancer patients decline entry into randomised clinical trials of adjuvant cancer therapy.
Many of the reasons why breast cancer patients decline entry to clinical trials could be addressed, as they tend to be a product of situational and process factors, rather than being rooted in deep-seated antipathy towards research.
Statements relating to randomisation were overwhelmingly the reasons for patients to decline entry into the trial.
Interestingly, many of these challenges have been highlighted in previous qualitative studies with COPD patients as important reasons why patients decline entry or withdraw from Pulmonary Rehabilitation Programmes.
The study outlines a number of factors that appear to influence a patient's decision to accept or decline entry into an RCT of cancer therapy.
These participants were contacted by mail and received an information leaflet explaining the aims and requirements of the study, a consent form which the patient signed, if they wished to participate, or alternatively a form to decline entry into the study and a stamped addressed envelope.
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Twenty-two consecutive patients, newly diagnosed with breast cancer, who had declined entry into a clinical trial were prospectively recruited from five outpatient breast cancer clinics in the North Trent Cancer Network.
Roped into a short-lived residency at the ill-fated Sankeys venture in New York and losing money amid rumours of fellow DJs being treated badly for taking on gigs with other clubs, the final straw was over Darius's concern about the alleged mistreatment of fans who had travelled for miles with tickets only to be declined entry to gigs.
Fourteen of these men (67%) completed a declined entry in the CROP study questionnaire.
Demographic details were taken with consent from those who declined entry to the study.
Only 3 of 14 patients chose the additional statements in the declined entry questionnaire.
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