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In other words, under SGoF's view there are no more than 70 p-values that could be declared as true effects in a 'reasonable way'.
The only caution that should be taken is that p-values above α can be declared as true effects if γ≠α (see the Real Data Illustration section).
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In case of rejection, SGoF declares as true effects the K−bα+1 smallest p-values.
By declaring as true effects the smallest 524 p-values one commits a FDR of about 16%.
Reviewing the album, Rolling Stone declared, "as much as any band in existence, Jane's Addiction is the true heir to Led Zeppelin".
I wonder what would happen if we all declared, as we know to be true, that crime is coming down in all western countries, with the occasional reverse in particular sorts of crime, and has being going that way for many years.
The ROC curve plots the trade-off between power (the proportion of true signals declared as influential) and FPR (the proportion of background SNPs declared as influential) when thresholding the SNP scores (log Ps or RMIPs) at different values.
An event of R True is declared as correctly predicted when it concerns the right part of the gene tree (node or edge) placed in the correct branch or node of the species tree (see [ 2] for more details).
For instance, the TRP is below 0.5 when the prior probability is less than 0.01, meaning that less than 50percentt of associations declared as being statistically significant are indeed true associations.
Therefore, we can conclude that in realistic scenarios, though we are not able to identify all truly differentially connected edges, those edges that are declared as differentially connected between states are very likely to be true findings.
In the power study, a QTL was declared as detected if the interval selected was within 5 cM either side of the true QTL position.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com