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Thus, processing of viral antigens in the MHC I and MHC II presentation pathway and recognition of MHC proteins are decisive targets for CMVs to evade effective clearance from the host.
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While some studies indeed implied a disease-intrinsic and possibly pathogenic role of antibodies directed against components of the myelin sheath, no unequivocal results on a decisive target antigen within the CNS persisted to date.
6.10pm GMT Out come the players Joe Root to open the bowling … 6.09pm GMT In other news, England's total is the only ODI score Kula Shaker (or anyone else for that matter?) ever sang about: Facebook Twitter Pinterest 5.53pm GMT Evening/afternoon/morning all For the first time in the series we have a decisive target.
Although we are still far from a comprehensive picture - especially, the identification of postulated, decisive target genes specifying particular cellular parameters is not sufficiently advanced - the concept has proven valuable.
These widely used mouse models are of first importance to identify decisive novel targets, to examine newly developed therapeutic tools and to determine/clarify the mode of action of these new molecules in vivo.
Western covert operations capability has been a rapidly expanding area of defense since 9/11, demanding greater expenditure from government budgets but proving decisive in targeting AQ across the globe.
In this context, clinicians play a decisive role targeting the patient subgroups that will most benefit from a particular intervention, thus achieving a more efficient use.
The difference may seem trivial, but the implications for intervention are not, because targeting a co-conspirator implies a more decisive intervention than targeting a pawn.
The results of these experiments were decisive: although shRNAs targeting peripheral activities showed no effect, those targeting three of the four enzymes responsible for hypusine synthesis showed potent tumour-promoting effects.
SPABBATS predicted four potential pathways for glutamate utilization that were decisive to suggest target genes for experimentation.
The statistical on-screen diversity targets become decisive if a commission has failed to satisfy another set of requirements such as giving airtime to underrepresented groups.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com