Sentence examples for decisive pathway from inspiring English sources

Interleukin-12 (IL-12) is recognized as a master regulator of adaptive type 1, cell-mediated immunity, the decisive pathway involved in protection against neoplasia and many viruses.

As regards mixtures, the study showed that due to an abundance of competing and interacting mechanistic steps, it is still difficult in that area to identify the toxicity pathway decisive for the resulting total effect and to draw (at least semi- quantitative conclusemi- quantitative

These pathways play decisive roles in cell fate decision in response to inflammation and infection.

Binding to Get3 is also a decisive step in the insertion pathway, as in its absence, secretory pathway TA proteins may insert into mitochondrial membranes.

The iTreg and Teff transcriptome profiling suggested FoxO family and FoxM1 transcription factor pathways as decisive molecular mechanisms regulating iTreg development and activation of Teffs, respectively.

Hence, the above findings point to a HOCl COX1 TXA2 pathway as being decisive in the prevention of MPO-dependent vasodilation in the SMAs (Fig. 7).

Among the elevated decisive genes of the interferon pathway is the transcription factor STAT1, which in turn induces the STAT1-dependent protein IRF1 thereby inhibiting NFκBp65.

It is certain that inhibition of the PDGFR β pathway plays a decisive role in the enhancement of radiosensitivity in breast cancer cell lines.

It demonstrated how patients' characteristics have a decisive impact on the CBRC pathway they use, influencing the choice of country and probably also the choice of centre within the country.

Better understanding of the pathways that lead to the stimulation of a given immune response and elucidation of the decisive molecules that initiate these pathways provide the basis for the design of novel adjuvants.

Today, ultrasound (US) plays a decisive role in the diagnostic pathways, with high sensitivity and specificity [ 6].