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But we would need to weigh in the balance the loss of our instant access to the single market, and our right to take the decisions that regulate it.
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For example, the proliferation vs. meiotic entry decision utilizes numerous proteins that regulate the translation and/or stability of target mRNAs [ 58, 59].
However, the genes that regulate cellular decisions and molecular mechanisms maintained by the TGFβ3 pathway throughout palatogenesis are predominantly unexplored.
Subsequent analysis has shown that these strains harbor a variety of sequence differences relative to N2 as a result of possible laboratory evolution (McGrath et al. 2009; Weber et al. 2010; McGrath et al. 2011), and our results show that hermaphrodite mating frequency can be a labile trait, possibly because of a large mutational target of genes that regulate reproductive decision.
According to one such model (Dijkstra and van Heuven 2002), a distinction should be made between a word identification system with access to a fully integrated multilingual lexicon, and a decision system that regulates control and the selection for action.
Stem or progenitor cell populations are often established in unique niche microenvironments that regulate cell fate decisions.
NOTCH proteins are single-pass trans-membrane receptors that regulate cell fate decisions during development.
NOTCH1 belongs to a unique family of type I transmembrane receptors that regulate cell fate decisions and differentiation during normal physiological development of many tissues.
The mechanisms that regulate proliferation, fate decisions and differentiation of hematopoietic stem cells (HSC) and thymic stem cells are highly complex.
Notch signalling is one of the key pathways in metazoans that regulate cell fate decisions in several systems, including the haematopoietic system.
Also, several oncogenic transcription factors that regulate cell-fate decision in HSCs and have been implicated in myeloid leukemia, such as MEIS1 and HOXA9, were found to be overexpressed in blast-crisis CML (Jamieson et al., 2004a, b).
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