Sentence examples for deciphering the target from inspiring English sources

Years later, after deciphering the target populations and translating the appropriate treatment strategies from the laboratory to the clinic, the drug became the 'gold standard' for endocrine therapy [ 45] and was credited with improving the survival of hundreds of thousands of women [ 12].

Despite these advances, the extraordinarily complex cellular responses to MYC expression has made it difficult to decipher the target genes that mediate these biological activities.

Toward this end, the "rules" being identified for naturally-occurring miRNAs may provide an inroad to deciphering the molecular targets of the identified functional small RNAs.

To this end, we used Target Scan and Ingenuity Pathway Analysis to decipher the predicted targets and pathways for the age-associated oncomirs/ts-mirs identified in our study.

Moreover, there are certain online resources like PASS Online (www.way2drug.com/passonline), SuperPred [45] and ChemProt server [46] for deciphering the biological potential and targets of different chemical compounds using information of existing drugs, environmental chemicals and natural products databases.

Modern molecular biology presents a novel approach and strategy to accelerate the genetic improvement of Chinese fir by molecular breeding programs based on deciphering the molecular genetic basis of target traits.

One of the best targets for deciphering the evolution of an island arc system is the Tanzawa Tonalites (4 9 Ma), in the intra-oceanic Izu Bonin Mariana arc.

Although substantial progress has been made in deciphering the histone substrate specificity and targeting mechanisms of HAT complexes (4, 5) such systems have been lacking for HDACs.

In the present study we focus on computationally deciphering the underlying network of miRNAs, their targets, and their control mechanisms that have an influence on OC development.

Deciphering the remote conditioning molecular mechanism may provide targets to develop therapeutics that can broaden the clinical application.

A fundamental difficulty lies in identifying miRNA targets as well as deciphering the exact mechanism of translational repression of mRNAs by these snippets.