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Hypocretin was the first protein directly linked to a true sleep disorder, and many labs jumped into deciphering its role in normal sleep.
Gaining insight into the genes regulated directly by Pax6 is fundamental in deciphering its role in the genetic regulatory networks governing embryonic development.
The mechanisms employed by TAp63 to induce senescence have important implications for deciphering its role as a tumor suppressor gene.
The aim of this work was developing an appropriate heterologous expression system for VanYn characterization to help deciphering its role in glycopeptide resistant cells.
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Akin to SphK1, in vivo active small molecule SphK2 selective inhibitors are necessary to decipher its role in physiology and disease states where S1P signaling might be awry.
Since the discovery of a second ER, ER beta (ER β) in 1996 (Kuiper et al, 1996), the general focus has been to decipher its role in biology and its corresponding clinical importance.
Sirtuin activation, however, specifically in SkM tissue or cells through overexpression in rodent models or supplementation of resveratrol/its analogues in humans, requires further investigation to decipher its role in negatively or positively regulating SkM mass.
Barry J. Marshall and Robin Warren, two Australian researchers who discovered the bacterium Helicobacter pylori and deciphered its role in gastritis and peptic ulcer disease, have been awarded this year's Nobel Prize in Physiology or Medicine.
Therefore, identification of proteins that interact with menin has significantly contributed to deciphering its biological roles.
Myelin around axons is currently widely studied by structural analyses and large-scale imaging techniques, with the goal to decipher its critical role in neuronal protection.
Further characterization of this candidate gene is needed to decipher its putative role in tonic immobility in Coturnix.
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CEO of Professional Science Editing for Scientists @ prosciediting.com