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Systematic large-scale data-set generation, using the same type of experiments that are used to decipher the function of single genes, are being applied on entire genomes.
The miRNA target mimicry and artificial miRNA technologies have proven to be useful tools to decipher the function of miRNAs of interest and should have broad applicability for improvement of rice disease resistance.
In an attempt to define the expression and decipher the function of individual members of the Nogo-66 receptor family, we previously reported the generation of selective rabbit polyclonal antibodies.
We have identified the major phosphorylation sites and used site-mutagenesis to decipher the function of direct phosphorylation of Nrf2 by MAPKs.
It is important to identify the genes that are specifically expressed in each cell type in order to systematically decipher the function of the trophoblast cells.
Thus, genetic and biochemical analyses like the ones described in this paper appear to be essential to decipher the function of specific isoforms, whose levels are moderately altered during Drosophila development.
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Future studies analyzing the occupancy of CTCF target sites by BORIS isoproteins and expression profiles of potential targets in germ cells and cancers will be needed to decipher the functions of BORIS isoproteins.
Jürgens and co-workers who were also based at the University of Tübingen—co-workers whoic, chemical and imaging approaches to decipher the functions of BIG1 to BIG4 (BIG1-4; Richter et al., 2014).
The completion of the Rice Genome Sequencing Project and high-throughput experimental methods have generated valuable data that can be used to identify proteins that interact with Hsps in rice, and consequently decipher the functions of Hsps.
During the process of using the fruit fly as a model to decipher the functions of zinc transporter dZIP13, we unexpectedly discovered dZIP13 physiologically acts as an iron exporter.
Experimental approaches for deciphering the function of human genes rely heavily on our ability to generate mutations in model organisms such as the mouse.
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