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To decipher the events that trigger apoptosis through the mitochondrial pathway, Bcl-2 family protein expression was analysed by western blot analysis after 4EGI-1 treatment.
Although it has been reported that glucose levels affect senescence, most of the experiments performed to decipher the events involved in OIS are performed with excess glucose (generally 25 mM).
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The differentiation capacities of PRLR KO and WT cell lines were assessed in order to decipher the molecular events by which PRLR signaling contributes to the commitment to the brown adipose phenotype.
As exemplified with GPCRs, the MDS projection technique is an important tool to compare orthologous sequence sets and to help decipher the mutational events that drove the evolution of protein families.
We took a candidate approach to decipher the molecular events that lead to TseL translocation.
These hypotheses could not then explain the difference of sensitivity in the cells lines tested and further researches are required to decipher the molecular events involved.
Genome-wide assessments of DNA methylation levels are now required to decipher the epigenetic events involved in the aggressive phenotype of glioblastoma, and to guide new treatment strategies.
Genome-wide assessments of DNA methylation are now necessary, to decipher the epigenetic events involved in the aggressive phenotype of GBM and to guide new treatment strategies.
To decipher the molecular events that determine cell fate in response to prolonged mitotic arrest, we investigated whether mitotic arrested cells were prone to trigger apoptosis signalling and how this signalling was controlled.
In the present study, our aim was to characterize the formation of the gut in P. caudatus and then, by comparing our data with the knowledge on C. elegans, D. melanogaster, and other bilaterians, to decipher the evolutionary events that occurred after cladogenesis of the nematode and arthropod lineages.
To decipher the molecular events that lead to the increased tumourigenesis associated with polyQ-huntingtin expression, we examined the gene expression patterns of MMTV-PyVT/ Hdh Q7/Q7 and MMTV-PyVT/ Hdh Q111/Q111 mammary tumours using Affymetrix Mouse Exon 1.0 ST microarrays (Fig 2).
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CEO of Professional Science Editing for Scientists @ prosciediting.com