Ovarian cancer is both heterogeneous and cytogenetically complex making it difficult to decipher the key genomic regions affected by CNA.
On the other hand, in the near future, sequencing of the total human exome could become a state-of-the-art technique for deciphering genetic variations affecting the outcome of HSCT.
Moreover, because it is easier to infer orthology from genic than intergenic regions, GC3 is also useful to reconstruct ancestral GC content and decipher processes affecting GC content on a phylogenetic scale (e.g., Romiguier et al. 2010; Lartillot 2013).
Our goals are to elucidate the roles of the mutant decorin in CSCD pathophysiology and to decipher the mechanism whereby mutant decorin affects matrix assembly.
This enhanced selection of self-specific foxp3+ T cells will certainly help to decipher signaling events affecting this population during their differentiation.
In an attempt to decipher the potential mechanisms by which Wee1 ablation affects cell growth, we performed caspase-activity assays after Wee1 siRNA treatment.
Despite much progress in our understanding of MSL interactions with each other or the male X chromosome, it remains a major challenge to decipher the mechanism by which the MSL complex affects gene expression.
Specifically, deciphering the pathways and genes affected by Nef in C.elegans may be helpful to understand the molecular pathways regulating HIV lipodystrophy which is characterized by hypertriglyceridemia, low HDL cholesterol, high total cholesterol, insulin resistance, altered energy expenditure and lipomatosis [47].
However, long-term analyses, over time-spans of centuries, are needed to decipher: the processes controlling the occurrence of disturbances; their affects on ecosystem properties; and, feedbacks to disturbance regimes [3], [4].
Although it has been reported that glucose levels affect senescence, most of the experiments performed to decipher the events involved in OIS are performed with excess glucose (generally 25 mM).
