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Interestingly, the amount of PD-1 expression and its engagement with ligands (PD-L1 and PD-L2) decides the threshold for T cell inactivation and the amount of cytokine production [39], [40], [41].
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After getting the list of monotonic genes, we can sort them by DEtotal or p-value in ascending order to identify those genes with stronger monotonic patterns, and decide the threshold for the gene list based on monotonicity.
Similar to Pfam and PlantTFDB 3.0, we used the bit scores output by HMMER 3.0 as a metric for deciding the thresholds for classifying domains.
To properly decide the thresholds for genome-wide significant/suggestive associations, a method of simpleM [ 64] was used to corrected the number of multiple tests.
ROC curve is a graphic arrangement to display the relationship between sensitivity and specificity, and it assists for best model selection by deciding the optimal threshold for the landslide assessment.
But if Mr Brown decides to raise the threshold for employees' NICs to match that for employers' contributions, he may be tempted to raise the upper earnings limit to pay for it.Besides reforming national insurance, Mr Brown has a manifesto commitment to honour: a starting rate of income tax of 10p in the pound.
The board decided to lower the threshold for activating a so-called poison pill after other companies lowered theirs, Ms. Collier said.
However, after several patients had experienced dose delays, it was decided to amend the threshold for an acceptable neutrophil count.
Mr. Bernanke is a "key witness" whose testimony would be "highly relevant," the judge continued, deciding that the situation meets the threshold for "extraordinarily circumstances" in which a government senior official would be called to testify.
Currently, the threshold for deciding which data is large or small defaults to 1 kB, but it can be overridden on the command line of the data acquisition software that records the data.
Therefore, we decided to use 0.7 as the threshold for adequate results on test-retest reliability to perform a pooled data analysis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com