Sentence examples for decelerate adaptation from inspiring English sources

This may seem paradoxical as under positive epistasis, recombination may be expected to decelerate adaptation [42].

Thus, interruption of a CIP monotherapy by DOR seems to have decelerated adaptation to CIP.

Hence, a disruption of a GEN monotherapy by CEF decelerated adaptation.

Moreover, the process of adaptation by mutation is not necessarily infinite, e.g., in bacteria diminishing returns of epistasis among beneficial mutations decelerates adaptation [ 148] and lead to an equilibrium of maximal efficiency.

This idea was recently tested using evolution experiments with laboratory strains of Escherichia coli (Fuentes-Hernandez et al. 2015; Schenk et al. 2015) and Staphylococcus aureus (Kim et al. 2014), consistently demonstrating that antibiotic alternation decelerates adaptation rates.

In contrast to the one-by-one model of clonal interference, which predicts decelerated adaptation rates and transient levels of genetic variation at large population size (N) and high beneficial mutation rate (μb), the multiple mutation model predicts that the both the speed of adaptation and variation in fitness increase logarithmically with N and with μb.

We further evaluated, whether antibiotic alternation decelerates adaptation to the individual components of the antibiotic pairs by collating the measurements of AUC inhibition for the eight (out of sixteen) seasons in the sequential treatment, during which populations were exposed to only one specific antibiotic (e.g. only the A seasons in a ABABABABABAB treatment).

This is because long generation times decelerate evolutionary adaptation processes, and the increased demand for resources of the individual will lead to lower population densities.

Although the fertility limitation decelerated the adaptation process of an organism indeed, it had little effect on the optimum mutation rate.

As a result, adaptation is considerably decelerated in the transforming population.

When fitness costs are decelerating, investing in this same mode of adaptation is not only the most efficient but also the least costly way to reinforce adaptation to host defenses.