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"debilitating illness" is a correct and usable phrase in written English.
It can be used to describe an illness that significantly weakens or impairs a person or their abilities. Example: The patient's debilitating illness prevented them from being able to work or carry out daily activities.
Exact(57)
Died on June 8 after a long debilitating illness.
(He died, after a debilitating illness, in 2006).
It is time for a thorough overhaul of public health policy toward this debilitating illness.
Alicia says her emotional struggles have been compounded by a debilitating illness.
Meanwhile, Groce spent nearly three decades in a wheelchair and was susceptible to debilitating illness.
As much a crime caper as a weepy about one man's fight against debilitating illness.
How does a child maintain youth and enthusiasm in the face of terrifying and debilitating illness?
He dismissed rumours that North Korea's leader, Kim Jong Un, is suffering from a debilitating illness.
Obviously, a person in extreme distress as a result of a debilitating illness is in a very different situation.
Even in late appearances, when his body was weakened by debilitating illness, the voice was still strong.
NOVAK--Naomi Rock, died on September 15, 2006 at New York University Hospital, following complications from a debilitating illness.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com