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The use of β2-adrenergic receptor agonists, or beta agonists, and their potential for an increased risk of asthma-related death were identified in the 1960's, and appears to have been related to the marketing of specific preparations of short-acting beta agonists (SABA) that are no longer in use today.
Factors independently associated with early or late in-hospital death were identified using a multinomial logistic regression model using the status alive as the reference category.
Four distinct but potentially overlapping trajectories to death were identified.
Risk factors for death were identified by multivariable logistic regression.
Causes of death were identified in 100% of subjects.
Key problems related to certification of death were identified.
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Evidence for 5 measures of death was identified (Table 5).
No meaningful relationship between etiology (TBI, hypoxia, others) and subsequent death was identified.
These two leading causes of death are identified as high priority areas in Healthy People 2010.
Additionally, any event that led to death was identified for adjudication [ 27].
No predominant cause of death was identified throughout the 5-year trial (see Additional file 1).
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