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Similarly, we did not explore the consequence of 15-PGDH inhibition on the concentration of other prostaglandins, but we showed that the cell death was considerably increased by the adding of PGE2 in the cell culture, demonstrating that PGE2 was at least partly responsible for the apoptosis induced.
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Death due to tumor progression was determined when tumor load was considerably increased, with replacement of normal liver tissue and/or invasion of large vessels possibly associated with liver failure and/or significant extrahepatic tumor spread.
Executive power was considerably increased at the expense of the National Assembly.
Overall, 28-day mortality of these patients was considerably increased.
Furthermore, 24-h post-SSE treatment, the apoptotic sub-G0/G1 peak was considerably increased to 35.56% and 55.05% in AGS and B16F10 cells, respectively, indicating that G2/M cell cycle arrest by SSE inhibited growth and consequently induced cell death.
Aside from targeting through scFv, bioactivity of death ligands can be considerably increased through oligomerization.
"Security measures have been considerably increased since the work was taken," added Calvocoressi.
Thus the network life-time can be considerably increased.
Blood vessels were tortuous and some were considerably increased in diameter.
This toxicity is considerably increased by small rises in temperature.
Ethanol yields can be considerably increased with higher yeast inoculum.
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CEO of Professional Science Editing for Scientists @ prosciediting.com