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Nowsheen, S. & Yang, E. S. The intersection between DNA damage response and cell death pathways.
The intervention of cell death pathways is therefore considered a potential therapeutic strategy.
These results suggest that iron can trigger cell death pathways by inducing intrinsic apoptotic proteins.
The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways.
Duprez, L., Wirawan, E., Berghe, T. V. & Vandenabeele, P. Major cell death pathways at a glance.
Altman, B.J. & Rathmell, J.C. Metabolic stress in autophagy and cell death pathways.
However, the exact mechanisms leading to the activation of cell death pathways are incompletely understood.
The compound alters microtubule dynamics inducing both intrinsic and extrinsic death pathways.
Inhibiting neuronal cell death pathways may slow the development of neurodegeneration.
Certain cytokines (and growth factors) seem to ameliorate HALI by affecting cell death pathways.
However, prolonged stress due to the buildup of these toxic proteins induces specific death pathways.
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